Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases

Chronic, non-communicable inflammatory skin diseases affect an estimated 20-25% of the population and include conditions such as atopic dermatitis, psoriasis, urticaria, lichen planus, and hidradenitis suppurativa, with causes ranging from genetic to environmental factors, and autoimmune responses that may be T cell or B cell driven. Despite improvements in diagnosis and treatment, challenges persist, including missed early diagnosis for rarer diseases, adverse events from systemic immunosuppression, unpredictable treatment responses, and the need for biomarkers to tailor individual patient treatments. The document suggests optimism for future advancements in addressing these challenges.