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GlossaryLichen Planus

inflammatory condition causing itchy, purplish skin and mucous membrane lesions

Lichen Planus is an inflammatory condition that affects the skin and mucous membranes, leading to purplish, itchy, flat-topped bumps. In the context of hair, it can cause a type of scarring alopecia known as lichen planopilaris, where the inflammation targets hair follicles, potentially leading to permanent hair loss.

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research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis

291 citations, January 2014 in “The Scientific World Journal”

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

research Lichen Planus

155 citations, June 2009 in “International Journal of Dermatology”

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

research Lichen Planus Pigmentosus and Its Variants: Review and Update

94 citations, October 2017 in “International Journal of Dermatology”

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Is There a Link?

86 citations, July 2012 in “British journal of dermatology/British journal of dermatology, Supplement”

There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.

research Treatment of Generalized Lichen Planus With Alefacept

52 citations, February 2006 in “Archives of Dermatology”

Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community I've tried everything and my hair is still thinning

in Chat 6 upvotes 10 months ago

The user has tried finasteride, oral minoxidil, iron supplements, vitamin D, and vitamin B12, but their hair is still thinning after 5 years. Another user suggested trying dutasteride.

community Clascoterone (Winlevi) Update for Canada

in Treatment 17 upvotes 2 years ago

Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

community He used Dutasteride for 20 years. Interview

in Treatment 109 upvotes 1 month ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 331 upvotes 10 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

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