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GlossaryBiomarkers

measurable indicators of a biological state or condition

Biomarkers, or biological markers, are measurable indicators of a biological state or condition. They can be used to diagnose diseases, monitor the progress of a condition, or evaluate the effectiveness of a treatment. For example, specific proteins in the blood can serve as biomarkers for heart disease or cancer.

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An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity

research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity

April 2018 in “Journal of Investigative Dermatology”

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

research Ultrahigh-Power Sonicator Lysis Enables Deep Proteomic Profiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery

November 2025 in “Analytical Chemistry”

A new method improves protein extraction from hair, helping identify potential biomarkers for fetal growth issues.

research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids

10 citations , March 2022 in “Communications biology”

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

research Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins

54 citations , January 2018 in “Scientific reports”

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

research Exploration of Integrated Targeted Serum and Hair Metabolomic Profiles in Men with Androgenetic Alopecia

February 2023 in “Singapore Medical Journal”

Men with androgenetic alopecia have unique metabolomic patterns that could help develop targeted treatments.

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community Bryan Johnson just dropped his anti hair loss formula

in Treatment 340 upvotes 2 years ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Dutasteride at 21 years old. Is it safe?

in Finasteride/Dutasteride 12 upvotes 2 years ago

A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.

community Realistically, how much PP405 will cost?

in Treatment 27 upvotes 1 year ago

PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

community Bruteforcing alopecia or the new advent of science progress

in Research/Science 21 upvotes 1 year ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

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