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Glossary Genetic Markers

specific DNA sequences indicating genetic traits or disease risks

Genetic markers are specific sequences in the DNA that can be used to identify individuals or species and can be associated with particular traits or diseases. They act like signposts within the genome, helping researchers locate genes linked to conditions such as alopecia, making it easier to study genetic predispositions and develop targeted treatments.

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Research

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SNP Markers: Analysis of Genetic Diversity and Identification of Genomic Regions in Pantaneiro and Texel Sheep Under Natural Selection

research SNP Markers: Analysis of Genetic Diversity and Identification of Genomic Regions in Pantaneiro Sheep and Texel Sheep Under Natural Selection

3 citations , September 2024 in “Frontiers in Bioscience-Scholar”

This study reported that Pantaneiro sheep from the Pantanal region of Brazil exhibit greater genetic variability and adaptability compared to the commercial Texel breed, highlighting their potential for further research and importance in Brazilian sheep farming.

research Genetic Markers of Male and Female Pattern Hair Loss

November 2005 in “Hair transplant forum international”

This paper discusses how studying hair follicles in the balding scalp could reveal fundamental biological processes, without reporting new experimental findings.

research Analyzing the role of ACE2, AR, MX1 and TMPRSS2 genetic markers for COVID-19 severity

9 citations , June 2023 in “Human Genomics”

This study found that higher levels of AR expression are linked to a decreased risk of severe COVID-19 in females, and identified ACE2, MX1, and TMPRSS2 as important molecular markers for COVID-19 management.

research MiR‐200c‐3p as a novel genetic marker and therapeutic tool for alopecia areata

7 citations , March 2024 in “Skin Research and Technology”

This study identified miR-200c-3p as influencing key genes in the EGFR resistance pathway, suggesting its potential theranostic role in addressing issues related to this pathway.

research Tru9I Variant as a Novel Genetic Marker for Vitamin D Deficiency in Alopecia Areata

March 2025 in “Clinical Cosmetic and Investigational Dermatology”

In this study, researchers found that the "U" allele of the Tru9I variant may be associated with low vitamin D levels and altered VDR gene activity in alopecia areata patients, while the "u" allele might have a protective role against developing the condition.

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Community Join

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community Which markers and nutrients could contribute to hair health in context of checking for deficiencies?

4 upvotes 1 year ago

Hair loss is primarily genetic, and nutrient deficiencies are unlikely to be the cause. DHT inhibitors can slow hair loss, but concerns about side effects are common.

community Finasteride stopped working. Losing ground on Dutasteride.

in Finasteride/Dutasteride 17 upvotes 4 months ago

The user started with Finasteride at 19, added Dutasteride and Minoxidil at 26, but continues to experience hair loss. Suggestions include checking health markers, considering genetics, and possibly increasing Minoxidil dosage.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 2 years ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community A man in his 80s with full head of hair.

473 upvotes 4 months ago

Genetics play a major role in hair loss, with some people keeping a full head of hair into old age without using treatments like minoxidil or finasteride. Many express frustration over their own hair loss and the perceived unfairness of genetic differences.

community Oral Minoxidil - The Hyper-Responder Concept

4 upvotes 10 months ago

Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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