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    Glossary Interferon Signature

    specific gene expression pattern induced by immune proteins

    The term "Interferon Signature" refers to a specific pattern of gene expression that is induced by interferons, which are proteins that play a crucial role in the immune response against viruses and other pathogens. This signature can be detected in various tissues and is often used as a biomarker to diagnose and monitor autoimmune diseases, infections, and certain types of cancer.

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    1. Type 1 interferon signature in the scalp lesions of alopecia areata British Journal of Dermatology · 2010 · 52 citations
    2. Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis Journal of the European Academy of Dermatology and Venereology · 2023 · 6 citations
    3. Epidermal γδ T cells, CD8 T cells and macrophages are increased in number in alopecia areata and express BST2 as part of an interferon-driven antiviral gene signature bioRxiv (Cold Spring Harbor Laboratory) · 2025
    4. Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature Lupus Science & Medicine · 2019 · 17 citations
    5. Developing human fetal skin demonstrates a unique lymphocyte signature bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    6. Immune signatures of psoriasis: Comparison of genetic expression profiles in psoriasis patients after therapy with biologic agents Journal of The American Academy of Dermatology · 2015
    7. Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications Preprints.org · 2025
    8. Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases Research Square (Research Square) · 2023
    9. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015 · 184 citations
    10. Novel TMEM173 Mutation and the Role of Disease Modifying Alleles Frontiers in immunology · 2019 · 47 citations
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    Community 2 of 11

    1. Does Apple cider vinegar interfere with oral minoxidil or finasteride? Reddit · 19 May 2025
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