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GlossaryPegylated Interferon

modified interferon with polyethylene glycol for prolonged therapeutic effect

Pegylated Interferon, often abbreviated as PEG-IFN, is a modified form of interferon used to treat certain viral infections and cancers. The "pegylation" process involves attaching polyethylene glycol (PEG) molecules to the interferon, which helps to prolong its presence in the bloodstream, reduce the frequency of dosing, and minimize side effects. This modification enhances the therapeutic efficacy and patient compliance compared to standard interferon treatments.

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research Psoriasis and Hepatitis C: Improvement with Interferon

January 2011 in “Annals of dermatology/Annals of Dermatology”

A woman's psoriasis improved after hepatitis C treatment with interferon, despite interferon's risk of worsening skin conditions.

Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review

research Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review

9 citations , November 2012 in “Hepatology Research”

A man lost all his hair permanently after hepatitis C treatment, a side effect not seen before.

research Pegylated-Interferon-Alpha 2a in Clinical Practice: How to Manage Patients Suffering from Side Effects

17 citations , February 2011 in “Expert Opinion on Drug Safety”

Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.

research Follow-Up of Adverse Drug Reactions from Peginterferon Alfa-2b—Ribavirin Therapy

32 citations , October 2004 in “Pharmacotherapy”

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.

research Widespread Dystrophic-Anagen Alopecia and Drug Eruption Due to Usage of PEG-IFN Alpha-2a/Ribavirin Combination Therapy

1 citations , January 2014 in “Hair therapy & transplantation”

The combination therapy of PEG-IFN α-2a and Ribavirin can cause widespread hair loss and skin reactions.

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