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    Glossary Small Interfering RNA

    molecule that silences specific genes by degrading their mRNA

    Small Interfering RNA (siRNA) is a type of molecule that can silence or "turn off" specific genes within a cell. It works by binding to a complementary messenger RNA (mRNA) sequence, leading to its degradation and preventing the production of the corresponding protein. This mechanism is often used in research and therapeutic applications to study gene function or to target and reduce the expression of disease-related genes.

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    1. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia (Alopecia Areata) in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008 · 69 citations
    2. The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis Frontiers in cell and developmental biology · 2022 · 3 citations
    3. Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6 Journal of Biological Chemistry · 2009 · 253 citations
    4. Keratin disorders: from gene to therapy 2011 · 109 citations
    5. Advances in transdermal siRNAs delivery: A review of current research progress Non-coding RNA Research · 2023 · 20 citations
    6. Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells Journal of Dermatological Science · 2011 · 19 citations
    7. OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis Journal of Investigative Dermatology · 2013 · 9 citations
    8. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75 Journal of Investigative Dermatology · 2015 · 6 citations
    9. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    10. Histidine decarboxylase expression influences the neofolliculogenesis of newborn mouse dermal cells Journal of Dermatological Science · 2012 · 2 citations
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