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    GlossarySmall Molecules

    low-weight compounds that easily enter cells to regulate processes

    Small molecules are low molecular weight organic compounds that can easily enter cells due to their small size. They are often used in medicine to regulate biological processes, including the treatment of diseases like cancer and alopecia, by interacting with specific proteins or enzymes within the body.

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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Mesotherapy

      technique to inject very small amounts of beneficial chemicals into the scalp

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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  143 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community How to mix Viagra for topical application?

      in Treatment  6 upvotes 1 year ago
      The conversation is about experimenting with topical Viagra or Cialis for hair loss, including methods for dissolving the tablets. The user is also using herbal oil massages and considering using Ethanol/Propylene Glycol for better dissolution.