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    GlossarySmall Molecules

    low-weight compounds that easily enter cells to regulate processes

    Small molecules are low molecular weight organic compounds that can easily enter cells due to their small size. They are often used in medicine to regulate biological processes, including the treatment of diseases like cancer and alopecia, by interacting with specific proteins or enzymes within the body.

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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Mesotherapy

      technique to inject very small amounts of beneficial chemicals into the scalp

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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 11 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  3 upvotes 3 months ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.