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Glossary Stress

body's response to demands, triggering hormone release

Stress is the body's response to any demand or challenge, whether physical, emotional, or psychological. It triggers the release of hormones like cortisol and adrenaline, which prepare the body to face the perceived threat. Chronic stress can lead to various health issues, including hair loss conditions like telogen effluvium and alopecia areata, as it disrupts the normal hair growth cycle and immune function.

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Research

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research Neuroimmunology of Stress: Skin Takes Center Stage

375 citations , July 2006 in “Journal of Investigative Dermatology”

This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.

research Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin

286 citations , June 2012 in “Nature Immunology”

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA_AReceptor Function and Seizure Susceptibility

269 citations , May 2002 in “Journal of Neuroscience”

This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.

research Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways

194 citations , March 2003 in “American Journal of Pathology”

This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.

research Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia

162 citations , August 2004 in “Journal of Investigative Dermatology”

This study suggests that stress negatively affects hair growth by inducing inflammation and early hair cycle transitions in mice, which might inform strategies for managing stress-related hair loss in humans.

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Community Join

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community Single stressful event enough to trigger recurring hair loss, study suggests

in Research/Science 224 upvotes 9 months ago

Stress can trigger hair loss, with treatments like minoxidil, finasteride, and dutasteride being used to manage it. Some users report improvement with medications like Lexapro, while others emphasize the impact of stress and life events on hair health.

community Stress supplements that do not increase shedding?

2 upvotes 10 months ago

Ashwagandha may lower cortisol but can cause hair loss. Alternatives like magnesium are suggested for stress without affecting hair.

community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice

30 upvotes 5 years ago

Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.

community (/r/science X-post): Stress may turn your hair grey. The appearance of grey hairs after periods of stress or skin damage could be the result of depletion of stem cells from the base of the hair follicle, according to a new study : science

4 upvotes 13 years ago

Stress can cause hair to turn grey due to stem cell depletion at the hair follicle base. Treatments discussed include Minoxidil, finasteride, and RU58841 for hair loss.

community Stressing out leads to hair loss. Staying positive and believing you will grow hair actually slows down MPB and can sometimes cause some hair growth.

14 upvotes 8 years ago

Staying positive and managing stress may slow hair loss, but treatments like finasteride, minoxidil, and dutasteride are essential for managing male pattern baldness. Stress can accelerate hair loss, but genetics play a significant role, and early treatment is crucial.

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Learn

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learn Lavender

Is lavender effective for hormonal hair loss or just stress? Lavender may help with stress-related hair loss but has limited evidence for hormonal hair loss.

learn Vitamin B6

Is Vitamin B6 helpful for stress-related or hormonal hair loss? Vitamin B6 may support overall health but lacks strong evidence for preventing hair loss.

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