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    Glossary Endoplasmic Reticulum Stress

    cellular condition where protein folding machinery becomes overwhelmed

    Endoplasmic Reticulum Stress (ER Stress) occurs when the endoplasmic reticulum, a cellular organelle responsible for protein folding and processing, becomes overwhelmed or dysfunctional. This can lead to the accumulation of misfolded or unfolded proteins, triggering a cellular response known as the Unfolded Protein Response (UPR) to restore normal function. If unresolved, ER stress can contribute to various diseases, including neurodegenerative disorders and diabetes.

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    1. Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis EMBO molecular medicine · 2019 · 11 citations
    2. Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing ACS Applied Materials & Interfaces · 2023 · 7 citations
    3. Melatonin protects cochlear hair cells from nicotine‐induced injury through inhibiting apoptosis, inflammation, oxidative stress and endoplasmic reticulum stress Basic & Clinical Pharmacology & Toxicology · 2021 · 5 citations
    4. A novel <i>MBTPS2</i> variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response American Journal of Medical Genetics Part A · 2021 · 5 citations
    5. Role of epigallocatechin-3-gallate from green tea in iron chelation and endoplasmic reticulum stress pathway in colorectal cancer cells 2018
    6. 616 Endoplasmic reticulum stress upregulates NKG2D ligands in the hair follicle 2017
    7. The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation Biomedicines · 2022
    8. Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome Journal of Ovarian Research · 2025 · 2 citations
    9. A bibliometric analysis of endoplasmic reticulum stress and atherosclerosis Frontiers in Physiology · 2024 · 1 citations
    10. OBESITY-RELATED FACTORS INVOLVED IN ENDOPLASMIC RETICULUM STRESS INDUCTION IN ADIPOCYTES Durham e-Theses (Durham University) · 2015
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