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GlossaryEndoplasmic Reticulum

network of membranes in cells for protein and lipid synthesis

The Endoplasmic Reticulum (ER) is a network of membranes within a cell that plays a crucial role in the synthesis, folding, modification, and transport of proteins and lipids. There are two types: Rough ER, which is studded with ribosomes and primarily involved in protein synthesis, and Smooth ER, which lacks ribosomes and is involved in lipid synthesis and detoxification processes.

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research Endoplasmic Reticulum in Health and Disease: The 12th International Calreticulin Workshop, Delphi, Greece

13 citations , November 2017 in “Journal of Cellular and Molecular Medicine”

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

research Endoplasmic Reticulum Stress at the Crossroads of Progeria and Atherosclerosis

11 citations , March 2019 in “EMBO molecular medicine”

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds With Endoplasmic Reticulum Stress-Relieving Properties For Promoted Scarless Wound Healing

research Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds With Endoplasmic Reticulum Stress-Relieving Properties For Promoted Scarless Wound Healing

7 citations , January 2023 in “ACS Applied Materials & Interfaces”

Probiotic-coated silk/alginate scaffolds help heal wounds faster and with less scarring.

research A Novel MBTPS2 Variant Associated With BRESHECK Syndrome Impairs Sterol-Regulated Transcription and the Endoplasmic Reticulum Stress Response

5 citations , October 2021 in “American Journal of Medical Genetics Part A”

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

Melatonin Protects Cochlear Hair Cells from Nicotine-Induced Injury Through Inhibiting Apoptosis, Inflammation, Oxidative Stress, and Endoplasmic Reticulum Stress

research Melatonin Protects Cochlear Hair Cells from Nicotine-Induced Injury Through Inhibiting Apoptosis, Inflammation, Oxidative Stress, and Endoplasmic Reticulum Stress

5 citations , July 2021 in “Basic & Clinical Pharmacology & Toxicology”

Melatonin may protect ear cells from damage caused by nicotine.

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community Don't use PP405 from everychem. it is likely fake.

in Research/Science 64 upvotes 5 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

in Minoxidil 37 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community PP405 vs Hair Cloning – Which Would Be Better for NW7 to NW1?

in Research/Science 19 upvotes 3 months ago

PP405 and hair cloning are discussed as potential treatments for reversing hair loss from Norwood 7 to Norwood 1. Hair cloning is seen as a more permanent solution, while PP405's effectiveness and long-term effects remain uncertain.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.