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Glossary Cancer

uncontrolled growth and spread of abnormal cells

Cancer, also known as a malignant tumor or malignant neoplasm, is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. If the spread is not controlled, it can result in death. Cancer can develop in almost any part of the body and often forms a mass called a tumor, although not all cancers form tumors (e.g., leukemia). The study and treatment of cancer fall under the field of oncology.

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Research

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Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.

research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer

211 citations , May 2018 in “Trends in cell biology”

This review explores recent insights into the diverse cell populations involved in skin development, homeostasis, wound healing, and cancer progression but reports no new results.

research Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study

147 citations , October 2021 in “Cancer Communications”

This study found that the novel anti-HER2 antibody RC48 demonstrated promising activity and manageable safety in patients with HER2-overexpressing, advanced gastric or gastroesophageal junction cancer after at least two prior chemotherapy lines.

research Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

145 citations , May 2008 in “Cancer Science”

This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.

research Normal stem cells and cancer stem cells: similar and different

126 citations , April 2010 in “Seminars in Cancer Biology”

This review discusses the similarities and differences between normal stem cell proliferation and cancer cell oncogenesis and concludes that understanding these mechanisms could improve cancer treatment strategies, but it reports no novel findings.

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Community Join

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community Concerns regarding topical fin application

74 upvotes 2 months ago

Topical finasteride, specifically Fynzur spray, is used for diffuse thinning in long hair, but many find the cone applicator ineffective and suggest applying directly to the scalp. Some users recommend oral finasteride for more even results, while others combine it with minoxidil for better effectiveness.

community Concern about my hair loss escalation

in Transgender 1 year ago

The user is experiencing significant hair loss and has tried treatments like PRP therapy, topical and oral Minoxidil, Finasteride, and dietary changes, with limited success. They are concerned about losing more hair before a scheduled hair transplant and are advised to postpone the transplant to allow medications more time to work.

community concerns about starting minoxidil

1 upvotes 5 years ago

An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.

community Cancelled hair transplant update 9 months.

269 upvotes 5 years ago

Microneedling combined with Minoxidilmax Essengen 6 (minoxidil and finasteride) and Nizoral shampoo led to impressive hair regrowth. The user achieved significant results without oral finasteride, using a Dr. Pen A7 for microneedling.

community A concern regarding the upcoming androgen degrader drug GT20029

11 upvotes 1 year ago

GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

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Learn

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learn Hair Transplant

Can a hair transplant cause cancer? Hair transplants do not cause cancer according to most providers.
How can I manage pain after a hair transplant? Use prescribed medications, over-the-counter pain relievers, and cold compresses to manage pain.

learn sh-Polypeptide-7

Are there any safety concerns or allergic reactions associated with sh-Polypeptide-7 in topical hair products? There are no published human studies on sh-Polypeptide-7 itself, so its safety is unestablished; research on cosmetic peptides as a class reports low irritation and rare allergy, and dermatologists advise patch testing a new scalp product.

learn tamsulosin

Should people experiencing hair loss be concerned about using tamsulosin-based medications? Tamsulosin is not known to cause or worsen hair loss.

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

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Clinics

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