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Glossary Cancer Progression

process where cancer cells grow, spread, and become more aggressive

Cancer progression, also known as tumor progression or neoplasm progression, refers to the process by which cancer cells grow, spread, and become more aggressive over time. This involves a series of genetic and cellular changes that enable the tumor to invade surrounding tissues, evade the immune system, and potentially metastasize to distant organs. Understanding cancer progression is crucial for developing effective treatments and improving patient outcomes.

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Research

5 / 1000+ results

research Cell-intrinsic mechanisms governing stem cell quiescence and regulating cancer progression in mammalian skin

January 2015 in “CU Scholar (University of Colorado Boulder)”

This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.

research Icariside II inhibits gastric cancer progression by suppressing the Wnt/β-catenin signaling pathway

1 citations , May 2025 in “Cytotechnology”

This study observed that Icariside II, an extract from Epimedium brevicornu Maxim, can inhibit the growth of gastric cancer in cell lines and mouse models by promoting apoptosis and suppressing the Wnt/β-catenin signaling pathway, with minimal toxicity to normal gastric cells.

research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence

3 citations , September 2020 in “Bladder cancer”

In this study, 5α-reductase inhibitors were found to have no significant impact on preventing tumorigenesis or progression in in vitro models of urothelial cancer.

research DEFINING THE ROLE OF ABI1 GENE IN PROSTATE CANCER PROGRESSION AND TREATMENT RESISTANCE

January 2024 in “Wiadomości Lekarskie”

This study reports that Abelson Interactor 1 (ABI1) regulates androgen receptor transcription in prostate cancer, identifying it as a potential target for new therapies addressing treatment resistance.

research Label-Free Monitoring of Endometrial Cancer Progression Using Multiphoton Microscopy

3 citations , July 2024 in “Annals of Biomedical Engineering”

This study found that multiphoton microscopy imaging allows for detailed observation and quantitative analysis of collagen alterations in the progression of endometrial cancer, potentially offering a faster, more accurate method for early diagnosis compared to current protocols.

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Community Join

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community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community Can i counter creatine with finasteride? Will it hinder my progression on fin?

35 upvotes 3 years ago

Creatine might increase DHT levels, potentially affecting hair loss, but its impact is debated. Some users experience hair shedding with creatine despite using finasteride, while others notice no change.

community Kintors interim report from 9-2-24 for everyone whos interested

32 upvotes 2 years ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community 9 months in….back from the dead!

in Progress Pictures 2044 upvotes 1 year ago

A user experienced significant hair regrowth after 9 months using 1mg finasteride and daily topical minoxidil, with dandruff as the only side effect. They stressed consulting a healthcare professional before starting treatment.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 2 years ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

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