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    GlossaryCancer-Associated Fibroblasts

    specialized cells in tumors that support cancer growth and spread

    Cancer-Associated Fibroblasts (CAFs) are specialized cells found within the tumor microenvironment that play a crucial role in cancer progression. They support tumor growth by remodeling the extracellular matrix, promoting angiogenesis (formation of new blood vessels), and secreting signaling molecules that enhance cancer cell survival and invasion.

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      chemical that might completely regrow follicles from hair transplant extractions

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 3 weeks ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community The most nuclear stack possible

      in Satire  41 upvotes 7 months ago
      A user humorously suggests an extreme hair loss treatment regimen involving multiple medications and therapies, including Dutasteride, Minoxidil, RU58841, and others, claiming it would prevent hair loss but with potential side effects like gynecomastia. The conversation highlights concerns about safety, side effects, and the effectiveness of such a comprehensive approach.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.