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GlossaryNasopharyngeal carcinoma

cancer originating in the upper part of the throat

Nasopharyngeal carcinoma (NPC) is a type of cancer that originates in the nasopharynx, which is the upper part of the throat located behind the nose. It is relatively rare and is often associated with genetic factors, Epstein-Barr virus (EBV) infection, and certain dietary habits. NPC can cause symptoms such as nasal congestion, nosebleeds, hearing loss, and swollen lymph nodes in the neck. Early detection and treatment, which may include radiation therapy, chemotherapy, or surgery, are crucial for improving outcomes.

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research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies

46 citations, February 2012 in “Oncology Reports”

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

research Perspectives in Head and Neck Medical Oncology

4 citations, January 2018 in “Cancer treatment and research”

The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.

The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis

research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis

October 2024 in “Frontiers in Oncology”

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

research Molecular Mechanisms of Viral Oncogenesis in Humans

141 citations, August 2018 in “Nature Reviews Microbiology”

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

research Hair Keratin KRT81 Is Expressed in Normal and Breast Cancer Cells and Contributes to Their Invasiveness

24 citations, April 2017 in “Oncology Reports”

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

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