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Glossary Paraneoplastic Alopecia

hair loss caused by body's immune response to cancer

Paraneoplastic Alopecia is hair loss that occurs as a result of an underlying cancer, rather than from the cancer treatment itself. This type of alopecia is often associated with internal malignancies, where the body's immune response to the tumor mistakenly attacks hair follicles, leading to hair loss.

Related Terms

Feline Paraneoplastic Alopecia

Research

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research A case of feline paraneoplastic alopecia with secondary Malossezia‐associated dermatitis

57 citations , August 1998 in “The journal of small animal practice/Journal of small animal practice”

This study reported that Malassezia-associated dermatitis can cause pruritus in cats with feline paraneoplastic alopecia.

research Resolution of paraneoplastic alopecia following surgical removal of a pancreatic carcinoma in a cat

52 citations , January 1999 in “Journal of Small Animal Practice”

This case study of a cat with pancreatic carcinoma and paraneoplastic alopecia found that removing the internal tumor reversed hair loss, but symptoms reappeared as the cancer metastasized.

research Paraneoplastic alopecia associated with internal malignancies in the cat

48 citations , March 1997 in “Veterinary Dermatology”

This report describes a paraneoplastic alopecia in four cats associated with internal malignancy, confirming previous findings of a syndrome linking ventral alopecia and metastatic carcinomas.

research Putative paraneoplastic alopecia in a cat with apocrine adenocarcinoma

1 citations , November 2024 in “Veterinary Dermatology”

This case study reported that a 13-year-old cat with paraneoplastic alopecia due to an intraabdominal apocrine adenocarcinoma exhibited ventrally distributed alopecia and shiny skin, with necropsy showing telogenisation and miniaturisation of the hair follicles.

research Resolution of paraneoplastic alopecia areata following nivolumab in a patient with metastatic melanoma

1 citations , June 2023 in “JAAD case reports”

This study reviews potential immune targets within hair follicles in alopecia areata, suggesting they may be associated with keratinocytes or melanocytes, and notes possible induction triggers like viruses and infections.

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