Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
August 2023
in “
bioRxiv (Cold Spring Harbor Laboratory)
”
basal cell carcinoma BCC optical coherence tomography single cell RNA sequencing spatial global transcriptional profiling in situ sequencing fibroblasts pericytes POSTN+ subpopulation RGS5+ pericytes hair follicles cancer-associated fibroblasts vascular remodeling stromal expansion skin cancer OCT RNA sequencing transcriptional profiling sequencing
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on biorxiv.org →