Search
for

    Glossary Basal Cell Carcinoma

    most common skin cancer, originating in basal epidermal cells

    Basal Cell Carcinoma (BCC) is the most common type of skin cancer, originating in the basal cells, which are found in the deepest layer of the epidermis. It typically appears as a small, shiny bump or nodule on sun-exposed areas of the skin, such as the face and neck, and is usually caused by long-term exposure to ultraviolet (UV) radiation from the sun or tanning beds. While BCC rarely metastasizes, it can cause significant local damage if not treated promptly.

    Related Terms

    Research 10 of 1000+

    1. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000 · 380 citations
    2. Identification of the cell lineage at the origin of basal cell carcinoma Nature Cell Biology · 2010 · 351 citations
    3. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000 · 333 citations
    4. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations Journal of Clinical Investigation · 2011 · 178 citations
    5. Basal cell carcinoma — molecular biology and potential new therapies Journal of Clinical Investigation · 2012 · 146 citations
    6. Cytokeratin 15 expression in trichoepitheliomas and a subset of basal cell carcinomas suggests they originate from hair follicle stem cells Journal of Cutaneous Pathology · 1999 · 133 citations
    7. Keratin expression in basal cell carcinomas British Journal of Dermatology · 1992 · 128 citations
    8. Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma ˜The œoncologist · 2016 · 127 citations
    9. Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle Archives of Dermatological Research · 1999 · 107 citations
    10. A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy Nature · 2018 · 105 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →