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GlossaryVismodegib

medication treats skin cancer by inhibiting Hedgehog signaling pathway

Vismodegib is a medication used to treat basal cell carcinoma, a type of skin cancer. It works by inhibiting the Hedgehog signaling pathway, which is involved in the growth and spread of cancer cells. This drug is particularly useful for patients with advanced stages of the disease or those who cannot undergo surgery or radiation.

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research Managing Adverse Events Associated with Vismodegib in the Treatment of Basal Cell Carcinoma

28 citations , September 2016 in “Future oncology”

Adverse events from vismodegib can be managed effectively to ensure optimal treatment.

research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma

25 citations , January 2021 in “Journal of drugs in dermatology”

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects

research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects

8 citations , May 2019 in “Journal of dermatological treatment”

Vismodegib is effective for basal cell carcinoma but has severe side effects.

research Experiences with SMO Antagonist Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma

September 2017

Vismodegib effectively treats advanced basal cell carcinoma but requires careful management of serious side effects.

research Unique Tumor Heterogeneity Within a Single Locally Advanced Basal Cell Carcinoma Resulting in Partial Response Despite Continuous Vismodegib Treatment

1 citations , July 2018 in “Dermatologic Surgery”

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