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    Glossary Vismodegib

    medication treats skin cancer by inhibiting Hedgehog signaling pathway

    Vismodegib is a medication used to treat basal cell carcinoma, a type of skin cancer. It works by inhibiting the Hedgehog signaling pathway, which is involved in the growth and spread of cancer cells. This drug is particularly useful for patients with advanced stages of the disease or those who cannot undergo surgery or radiation.

    Research 10 of 96

    1. Managing adverse events associated with vismodegib in the treatment of basal cell carcinoma Future oncology · 2016 · 28 citations
    2. A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma Journal of drugs in dermatology · 2021 · 25 citations
    3. Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects Journal of dermatological treatment · 2019 · 8 citations
    4. Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database Frontiers in Pharmacology · 2025 · 3 citations
    5. Disproportionality analysis comparing safety profiles of sonidegib and vismodegib based on the FAERS database Scientific Reports · 2025 · 1 citations
    6. Unique Tumor Heterogeneity Within a Single Locally Advanced Basal Cell Carcinoma Resulting in Partial Response Despite Continuous Vismodegib Treatment Dermatologic Surgery · 2018 · 1 citations
    7. Experiences with Smo antagonist vismodegib for the treatment of locally advanced basal cell carcinoma 2017
    8. A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy Nature · 2018 · 105 citations
    9. Targeting of Smoothened for therapeutic gain Trends in Pharmacological Sciences · 2014 · 105 citations
    10. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
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