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Glossary Carcinomas

Carcinomas are a type of cancer that originates in epithelial cells, which line the surfaces of organs and structures throughout the body. While not directly related to hair loss, certain carcinomas, particularly those affecting the scalp or skin, can lead to hair loss due to localized treatments like radiation or surgical removal. Additionally, some systemic treatments for cancer, such as chemotherapy, can cause widespread hair thinning or loss as a side effect. Understanding carcinomas is important in the context of hair biology, as they can impact the health of hair follicles and the scalp environment.

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research Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion.

99 citations , February 2000 in “PubMed”

This study found that overexpression of PKCepsilon in transgenic mice reduced papilloma development but accelerated carcinoma formation in a skin tumor promotion model.

research 409 ANDROGEN RECEPTOR GENE POLYMORPHISM (SNP RS6152) – ITS RELATIONSHIP TO ANDROGEN-SENSITIVE GENES EXPRESSION IN BENIGN PROSTATIC HYPERPLASIA, CARCINOMA OF THE PROSTATE AND ANDROGENETIC ALOPECIA

March 2011 in “European Urology Supplements”

Gene variation affects prostate issues and hair loss.

research Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases

80 citations , June 2000 in “Modern Pathology”

Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.

research Immunohistochemical demonstration of breast‐derived and/or carcinoma‐associated glycoproteins in normal skin appendages and their tumors

71 citations , February 1992 in “Journal of Cutaneous Pathology”

This study found that monoclonal antibodies identified distinct staining patterns in benign and malignant skin appendage tumors, highlighting their potential as markers for analyzing skin tumors.

research Resolution of paraneoplastic alopecia following surgical removal of a pancreatic carcinoma in a cat

52 citations , January 1999 in “Journal of Small Animal Practice”

This case study of a cat with pancreatic carcinoma and paraneoplastic alopecia found that removing the internal tumor reversed hair loss, but symptoms reappeared as the cancer metastasized.

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