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    Glossary Cutaneous Squamous Cell Carcinoma

    type of skin cancer originating in outer squamous cells

    Cutaneous Squamous Cell Carcinoma (cSCC) is a type of skin cancer that originates in the squamous cells, which are flat cells located in the outer layer of the skin (epidermis). It often appears as a red, scaly patch, open sore, or wart-like growth that may crust or bleed, and it can develop on sun-exposed areas of the body. If left untreated, cSCC can grow larger and potentially spread to other parts of the body, making early detection and treatment crucial.

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    1. miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma Oncogene · 2021 · 30 citations
    2. Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Oncotarget · 2018 · 11 citations
    3. Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals Carcinogenesis · 2015 · 11 citations
    4. Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma EBioMedicine · 2021 · 7 citations
    5. Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis Frontiers in genetics · 2019 · 6 citations
    6. Invasive cutaneous squamous cell carcinoma of scalp: A case report Annals of Medicine and Surgery · 2022 · 2 citations
    7. MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells Viruses · 2022 · 2 citations
    8. Postoperative Radiotherapy for Cutaneous Squamous Cell Carcinoma in Patients With Microscopic Residual Disease JAMA Dermatology · 2020 · 2 citations
    9. High-risk cutaneous squamous cell carcinoma in a Japanese allogeneic bone marrow transplant recipient on long-term voriconazole The Journal of Dermatology · 2017 · 2 citations
    10. Successful in situ 5-aminolevulinic acid photodynamic therapy in a 53-year-old female with cutaneous squamous cell carcinoma Journal of Zhejiang University SCIENCE B · 2025 · 1 citations
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