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Glossary Cutaneous Mosaicism

condition where skin patches have different genetic makeups

Cutaneous mosaicism refers to a condition where different patches of skin on the same individual have distinct genetic makeups. This occurs due to mutations in skin cells during early development, leading to areas of skin that can vary in color, texture, or susceptibility to certain conditions. For professionals, it is important to note that this phenomenon can result from postzygotic mutations and can manifest in various dermatological patterns such as lines of Blaschko.

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Research

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research Porokeratotic adnexal ostial nevus: a paradigm of cutaneous mosaicism

February 2022 in “Authorea (Authorea)”

This report presents a case of a seven-year-old girl with porokeratotic adnexal ostial nevus manifesting as hyperkeratotic verrucous papules on her left foot.

research Analogs of human genetic skin disease in domesticated animals

3 citations , March 2017 in “International journal of women’s dermatology”

This review discusses genetic skin diseases in humans and animals, offering a resource for memorization and exploring animal models' role in understanding human disease mechanisms; it reports no new clinical results.

research Acne Syndromes and Mosaicism

1 citations , November 2021 in “Biomedicines”

This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.

research Segmental cherry angiomas associated with extragenital lichen sclerosus: A report of two cases

January 2011 in “Journal of The American Academy of Dermatology”

Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.

research Becker's nevus associated with chromosomal mosaicism and congenital adrenal hyperplasia

32 citations , April 1994 in “Journal of the American Academy of Dermatology”

This report presents the second known case of erythema nodosum without typical associated conditions, which could be linked to mycoplasma infection, although no testing was conducted to confirm this in the patient.

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DCSI - Dermatology & Cutaneous Surgery InstituteWellington, FL · US

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