Flavonoids with Two Hydroxyl Groups in the B-Ring Promote Pigmented Hair Regeneration

    August 2019 in “ Biological & Pharmaceutical Bulletin ”
    Nobuyuki Taguchi, Minoru Yuriguchi, Takuya Ando … Takahiro Kunisada
    Studysummary This study found that flavonoids with two hydroxyl groups in their B-ring, such as sterubin and luteolin, supported the regeneration of pigmented hair after skin injury, unlike those with one hydroxyl group.
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    Research cited in this study 5

    1. Never Too Old to Regenerate? Wound-Induced Hair Follicle Neogenesis After Secondary Intention Healing in a Geriatric Patient Journal of Tissue Viability · 2018
    2. Pigmentation of Regenerated Hairs After Wounding Journal of Dermatological Science · 2016
    3. EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling Cell Reports · 2016
    4. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    5. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007

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