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Glossary Secondary Syphilis

second stage of syphilis with rashes and mucous membrane lesions

Secondary Syphilis, also known as the secondary stage of syphilis, is a phase of the sexually transmitted infection caused by the bacterium Treponema pallidum. This stage typically occurs weeks to months after the initial infection and is characterized by symptoms such as skin rashes, mucous membrane lesions, and flu-like symptoms. It is highly infectious during this period and can affect multiple organ systems, making early diagnosis and treatment crucial to prevent further complications.

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research Secondary Syphilis in Cali, Colombia: New Concepts in Disease Pathogenesis

82 citations , May 2010 in “PLoS neglected tropical diseases”

This study provides quantitative evidence that secondary syphilis is highly endemic in Cali, Colombia, and many untreated patients have high numbers of circulating Treponema pallidum spirochetes.

research Hair and Scalp Manifestations in Secondary Syphilis: Epidemiology, Clinical Features and Trichoscopy

45 citations , January 2015 in “Dermatology”

In this study, 41.6% of patients with secondary syphilis exhibited syphilitic alopecia, with the 'moth-eaten' pattern most commonly observed through trichoscopy.

research Diffuse pattern essential syphilitic alopecia: an unusual form of secondary syphilis

10 citations , July 2012 in “International Journal of Dermatology”

This article addresses diffuse pattern essential syphilitic alopecia as an unusual form of secondary syphilis but provides no new clinical findings.

research Folliculotropic non-alopecic secondary syphilis

6 citations , September 2011 in “Journal of the American Academy of Dermatology”

This report describes a case of secondary syphilis with an unusual folliculocentric papular eruption in an HIV-positive patient, underlining the diagnostic challenges and importance of biopsy with treponemal staining in such cases.

research Immune reconstitution inflammatory syndrome associated with secondary syphilis: dermatologic, neurologic and ophthalmologic compromise in an HIV patient

5 citations , January 2019 in “International Journal of STD & AIDS”

This report discusses a rare case where immune reconstitution inflammatory syndrome in an HIV patient led to dermatologic, ophthalmologic, and neurologic complications due to secondary syphilis.

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community Secondary shedding, 6 months into oral minoxidil/finasteride 3mg chewables

55 upvotes 4 months ago

The user experienced significant hair regrowth and increased density after six months of using oral minoxidil and finasteride chewables, despite going through a secondary shedding phase. The only side effect mentioned was restlessness, and the user feels healthier overall.

community Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis

11 upvotes 3 weeks ago

Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.

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