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GlossaryHypogonadotropic Hypogonadism

condition where low hormone signals from the brain reduce sex hormone production

Hypogonadotropic Hypogonadism (HH) is a condition where the gonads (testes in men and ovaries in women) produce insufficient sex hormones due to a problem with the hypothalamus or pituitary gland, which are responsible for signaling the gonads to function. This can lead to delayed puberty, infertility, and other hormonal imbalances.

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research Physiology of Male Gonadotropic Axis and Disorders of Sex Development

January 2017 in “Springer eBooks”

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Corticotropin Releasing Factor-1 Receptor Antagonism Associated With Favorable Outcomes of Male Reproductive Health Biochemical Parameters

research Corticotropin Releasing Factor-1 Receptor Antagonism Associated With Favorable Outcomes of Male Reproductive Health Biochemical Parameters

May 2023 in “Frontiers in Endocrinology”

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

research The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

7 citations , January 2015 in “Case reports in genetics”

Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.

research SUN-287: A Case of Ectopic Neurohypophysis

April 2020 in “Journal of the Endocrine Society”

The patient with a misplaced pituitary gland and interrupted pituitary stalk is being treated with hormone replacement.

research Panhypopituitarism Induced by CTLA-4 and PD-1/PD-L1 Inhibitor Immunotherapy

November 2022 in “Journal of the Endocrine Society”

Immunotherapy for cancer caused a patient to develop a condition affecting hormone production, requiring ongoing hormone replacement therapy.

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