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    Glossary Hypogonadotropic Hypogonadism

    condition where low hormone signals from the brain reduce sex hormone production

    Hypogonadotropic Hypogonadism (HH) is a condition where the gonads (testes in men and ovaries in women) produce insufficient sex hormones due to a problem with the hypothalamus or pituitary gland, which are responsible for signaling the gonads to function. This can lead to delayed puberty, infertility, and other hormonal imbalances.

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    Research 30 of 225

    1. Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study The Journal of Clinical Endocrinology & Metabolism · 2014 · 46 citations
    2. Idiopathic hypogonadotropic hypogonadism in a male runner is reversed by clomiphene citrate Fertility and sterility · 1997 · 41 citations
    3. Adult Onset Isolated Hypogonadotropic Hypogonadism- a Cause of Secondary Amenorrhea Journal of the Endocrine Society · 2021
    4. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013 · 2152 citations
    5. Polycystic Ovary Syndrome and Its Differential Diagnosis Obstetrical & Gynecological Survey · 2006 · 42 citations
    6. The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome Case reports in genetics · 2015 · 7 citations
    7. A case of hyperpigmentation and acanthosis nigricans by testosterone injections Human & experimental toxicology · 2014 · 6 citations
    8. Kallmann's syndrome: skeletal and psychological aspects of late diagnosis. PubMed · 2003 · 5 citations
    9. Diagnosis and Management of Infertility due to Anovulation Infertility · 2011 · 2 citations
    10. P-18 THREE BODY PROBLEM PATIENT: EHLER DANLOS SYNDROME COMBINED WITH HYPOPHOSPHATASIA AND FATTY ACID OXIDATION DEFECT JCEM Case Reports · 2025
    11. Corticotropin releasing factor-1 receptor antagonism associated with favorable outcomes of male reproductive health biochemical parameters Frontiers in Endocrinology · 2023
    12. ODP342 Panhypopituitarism Induced by CTLA-4 and PD-1/PD-L1 Inhibitor Immunotherapy Journal of the Endocrine Society · 2022
    13. SUN-287 A Case of Ectopic Neurohypophysis Journal of the Endocrine Society · 2020
    14. Physiology of Male Gonadotropic Axis and Disorders of Sex Development Springer eBooks · 2017
    15. Renal Carcinoma Presenting with Adrenocortical Insufficiency Due to a Pituitary Metastasis Annals of Clinical Biochemistry International Journal of Laboratory Medicine · 1998 · 20 citations
    16. Testosterone replacement in 49,XXXXY syndrome: andrological, metabolic and neurological aspects Endocrinology, diabetes & metabolism case reports · 2016 · 12 citations
    17. Abstract 14 Indian Journal of Endocrinology and Metabolism · 2014 · 9 citations
    18. Woodhouse-Sakati Syndrome Due to the Rare DCAF17 c.321+1G>A Mutation: The Second Case Report Worldwide Cureus · 2026
    19. SUN-208 Rare Case of 47XXY/46XX Mosaic Klinefelter Syndrome Journal of the Endocrine Society · 2019
    20. Alopecia universalis and Kallman’s Syndrome Dermatology · 1986 · 2 citations
    21. Puberty induction with recombinant gonadotropin: What impact on future fertility? Annales d Endocrinologie · 2022 · 2 citations
    22. Novel Mutation in the Hemojuvelin Gene (HJV) in a Patient with Juvenile Hemochromatosis Presenting with Insulin-dependent Diabetes Mellitus, Secondary Hypothyroidism and Hypogonadism American Journal of Case Reports · 2020 · 3 citations
    23. Menstrual Cycle Disturbances at Reproductive Age InTech eBooks · 2011
    24. Delayed Puberty Springer eBooks · 2016
    25. Ocular manifestations in a case of Kallmann syndrome – An interesting case report on isolated gonadotropin-releasing hormone deficiency Indian Journal of Ophthalmology - Case Reports · 2023
    26. Men??s Health Drugs in R & D · 1999
    27. Hypotrichosis 14: novel variants of the LSS gene in five Chinese families and insights from literature review Human Genomics · 2025
    28. CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism? The Journal of Sexual Medicine · 2013 · 29 citations
    29. Emerging medication for the treatment of male hypogonadism Expert Opinion on Emerging Drugs · 2012 · 77 citations
    30. Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male Urologic Clinics of North America · 2016 · 70 citations