SUN-287: A Case of Ectopic Neurohypophysis

    April 2020 in “ Journal of the Endocrine Society ”
    kehinde Matilda folawewo, MaKenzie Hodge, Nada Osman, Anteneh Zenebe, Vijaya Ganta, Wolali Odonkor, Gail Nunlee-Bland
    Studysummary This case report describes a 34-year-old woman with pituitary stalk interruption syndrome, highlighting the need for long-term follow-up due to potential progression from isolated hormonal deficiencies to pan-hypopituitarism. Our plain-language summary of this paper — not a Tressless recommendation.
    The document described a case of a 34-year-old woman with pituitary stalk interruption syndrome (PSIS), a congenital disorder of the pituitary gland. The patient presented with primary amenorrhea, short stature, and hypogonadotropic hypogonadism. MRI findings indicated ectopic neurohypophysis, and a DXA scan showed reduced bone mineral density. She was treated with hormonal replacement therapy and required long-term follow-up due to the potential progression to pan-hypopituitarism. The study highlighted the heterogeneous nature of PSIS and the importance of ongoing monitoring.
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