The Current and Emerging Role of Statins in the Treatment of Polycystic Ovary Syndrome: The Evidence to Date

    January 2024 in “ Medicina ”
    Tea Shehu Kolnikaj, Rok Herman, Andrej Janež, Mojca Jensterle
    Studysummary This review examines the pathogenesis of androgen excess and dyslipidemia in PCOS and the potential role of statins as a treatment but provides no new clinical results.
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    Research cited in this study 10

    1. The Lipid Profiles in Different Characteristics of Women with PCOS and the Interaction Between Dyslipidemia and Metabolic Disorder States: A Retrospective Study in Chinese Population Frontiers in Endocrinology · 2022
    2. Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing International Journal of Molecular Sciences · 2022
    3. Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome International Journal of Molecular Sciences · 2020
    4. Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review Egyptian Journal of Medical Human Genetics · 2019
    5. 5α-Reductase Activity in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis Reproductive Biology and Endocrinology · 2017
    6. Comprehensive Overview of Polycystic Ovary Syndrome Nature Reviews Disease Primers · 2016
    7. Diabetes and Cardiovascular Events in Women with Polycystic Ovary Syndrome: A 20-Year Retrospective Cohort Study Clinical Endocrinology · 2012
    8. Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred Because of Clinical Hyperandrogenism The Journal of Clinical Endocrinology and Metabolism · 2006
    9. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    10. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003

    Related research 4

    1. Current Aspects of Polycystic Ovary Syndrome: A Literature Review Revista Da Associacao Medica Brasileira · 2016
    2. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    3. The Diagnosis of Polycystic Ovary Syndrome in Adolescents American Journal of Obstetrics and Gynecology · 2010
    4. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004