TLDR Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
The study examined the effects of androgen treatment in adolescent males with hypogonadism, involving 150 participants. It found that androgen therapy significantly improved physical development, including increased muscle mass, bone density, and secondary sexual characteristics, along with psychological benefits such as improved mood and self-esteem. The research concluded that androgen treatment was effective and beneficial for adolescent males with hypogonadism, with minimal adverse effects reported. Various testosterone formulations were discussed, with intramuscular injections being the most common. The review emphasized the need for careful monitoring and personalized treatment approaches to optimize benefits and minimize risks.
15 citations,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
46 citations,
October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
54 citations,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
February 2023 in “IntechOpen eBooks” Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
72 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
21 citations,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
39 citations,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
