Benefits of Testosterone Replacement and Methods of Substitution

    February 2023 in “ IntechOpen eBooks
    Kenneth Ho
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    TLDR Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
    The document "Benefits of Testosterone Replacement and Methods of Substitution" discusses the various methods and benefits of testosterone replacement therapy. It is effective for managing testosterone deficiency and can be administered orally, nasally, transdermally, and intramuscularly. A new method, scrotal application of testosterone cream, has also been introduced. However, overuse can lead to adverse effects, especially in older, obese individuals with chronic cardiorespiratory disorders and lower urinary tract symptoms. Therefore, therapeutic monitoring is crucial. The document also discusses the role of testosterone in male development and the effects of testosterone deficiency. Testosterone replacement therapy has been shown to improve these symptoms and also have beneficial effects on metabolic derangements associated with type 2 diabetes. The document also mentions non-testosterone substitution options, such as the use of the plant Tribulus terrestris and Selective Androgen Receptor Modulators (SARMs), but these are not considered mainstream therapy.
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