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This study developed a reliable UHPLC-MS/MS method to measure flavonoids from Pinus massoniana needles in rat plasma for pharmacokinetics, aiding further research on their potential use in external preparations to prevent hair loss.

This study found that hair steroid analysis effectively detected increased hormone levels from both a single testosterone dose and laboratory-induced stress, revealing individual context factors like relationship status also impact hair hormone concentrations.

This research observed that oral testosterone replacement therapy significantly increases cardiovascular risk, while effects of injected or transdermal therapy on cardiovascular risk were not significant, prompting further investigation into these methods.

This review discusses advancements in using dissolving microneedle systems for transdermal delivery of traditional Chinese medicine, highlighting potential benefits for simplifying application, enhancing safety, and increasing efficacy, and underscores its possible impact on modernizing traditional medicine practices.

This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.