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research Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues

10 citations , October 2012 in “Andrology”

In this case study, researchers observed that steroidogenesis from adrenal androgens in prostate cancer tissues may explain progression in a 74-year-old man with low circulating testosterone.

research The effect of chemotherapy regimens in male germ cell tumors on the development of primary hypogonadism

November 2024 in “Scientific Reports”

In this study, researchers at a tertiary cancer center observed that many male germ cell tumor survivors experienced degrees of hypogonadism and erectile dysfunction, highlighting the clinical need to monitor endocrine health in cancer survivors.

research Gonadal Function Abnormalities in Sickle Cell Anemia

163 citations , November 1976 in “Annals of Internal Medicine”

This study found that adults with sickle cell anemia exhibited androgen deficiency due to primary testicular failure, and there was a significant correlation between erythrocyte zinc levels and serum testosterone.

research Alopecia universalis and Kallman’s Syndrome

2 citations , January 1986 in “Dermatology”

This letter discusses alopecia universalis and Kallman’s Syndrome, and offers no new clinical results.

research Abstract 14

9 citations , November 2014 in “Indian Journal of Endocrinology and Metabolism”

This case report describes a young female with a rare combination of 46,XX gonadal dysgenesis and MRKH syndrome, highlighting associated infertility challenges.

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community Why do I have the feeling that this subreddit is flooded by Kintor employees?

in Chat 132 upvotes 2 years ago

Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.

community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 1 year ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

community Primary Care Provider told me to not be concerned and just take biotin.

in Finasteride/Dutasteride 2 upvotes 1 year ago

A 19-year-old was advised by their primary care provider to take biotin for hair loss instead of minoxidil or finasteride due to potential side effects and age concerns. The user is considering seeking a second opinion from a dermatologist.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

133 upvotes 2 years ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

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