Development of Prostate Cancer in a Patient with Primary Hypogonadism: Intratumoral Steroidogenesis in Prostate Cancer Tissues

    October 2012 in “ Andrology ”
    Seiji Arai, Yasuhiro Shibata, Yasuhiro Nakamura … Kazuhiro Suzuki
    Studysummary In this case study, researchers observed that steroidogenesis from adrenal androgens in prostate cancer tissues may explain progression in a 74-year-old man with low circulating testosterone.
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    Research cited in this study 1

    1. Steroid 5α-Reductases and 3α-Hydroxysteroid Dehydrogenases: Key Enzymes in Androgen Metabolism Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism · 2001