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    Glossary Secondary Syphilis

    second stage of syphilis with rashes and mucous membrane lesions

    Secondary Syphilis, also known as the secondary stage of syphilis, is a phase of the sexually transmitted infection caused by the bacterium Treponema pallidum. This stage typically occurs weeks to months after the initial infection and is characterized by symptoms such as skin rashes, mucous membrane lesions, and flu-like symptoms. It is highly infectious during this period and can affect multiple organ systems, making early diagnosis and treatment crucial to prevent further complications.

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    1. Secondary Syphilis in Cali, Colombia: New Concepts in Disease Pathogenesis PLoS neglected tropical diseases · 2010 · 82 citations
    2. Hair and Scalp Manifestations in Secondary Syphilis: Epidemiology, Clinical Features and Trichoscopy Dermatology · 2015 · 45 citations
    3. Diffuse pattern essential syphilitic alopecia: an unusual form of secondary syphilis International Journal of Dermatology · 2012 · 10 citations
    4. Folliculotropic non-alopecic secondary syphilis Journal of the American Academy of Dermatology · 2011 · 6 citations
    5. Immune reconstitution inflammatory syndrome associated with secondary syphilis: dermatologic, neurologic and ophthalmologic compromise in an HIV patient International Journal of STD & AIDS · 2019 · 5 citations
    6. Secondary Syphilis in Human Immunodeficiency Virus (HIV)-Infected Men Who Have Sex with Men (MSM): A Case Report Berkala Ilmu Kesehatan Kulit dan Kelamin · 2020 · 4 citations
    7. Secondary Syphilis in Patients Treated at the City Institute for Skin and Venereal Diseases in Belgrade from 2010 to 2014 Serbian Journal of Dermatology and Venereology · 2015 · 3 citations
    8. Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report AIDS Research and Therapy · 2024 · 2 citations
    9. Diffuse Hair Loss in Secondary Syphilis in HIV Positive Man: Case Report Acta Facultatis Medicae Naissensis · 2012 · 2 citations
    10. Secondary Syphilis in a 12-Year-Old Girl Misdiagnosed as Pityriasis lichenoides et varioliformis acuta: A Case Report Clinical Cosmetic and Investigational Dermatology · 2021 · 1 citations
    11. Clinical and Dermoscopic Correlation in Secondary Syphilis: A Report of Three Cases Indian Dermatology Online Journal · 2026
    12. Case Report: Secondary syphilitic alopecia following non-penetrative sexual contact: a case of initial misdiagnosis Frontiers in Medicine · 2026
    13. Overlapping Primary and Secondary Syphilis in Human Immunodeficiency Virus (HIV) Patient Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya · 2020 · 1 citations
    14. Alopecia Areata in a Patient Undergoing Treatment for Secondary Syphilis: A Diagnostic Challenge Cureus · 2026
    15. Moth-eaten alopecia as a sole manifestation of secondary syphilis in an adolescent: Role of a dermatologist Indian journal of sexually transmitted diseases and AIDS · 2021
    16. Hair root studies in patients suffering from primary and secondary syphilis Acta dermato-venereologica · 1987 · 6 citations
    17. Syphilis: A great imitator Clinics in Dermatology · 2019 · 35 citations
    18. Syphilitic alopecia: uncommon trichoscopic findings Dermatology practical & conceptual · 2017 · 32 citations
    19. Dermatoscopic findings of syphilitic alopecia Anais Brasileiros de Dermatologia · 2020 · 11 citations
    20. Nonspecific diffuse alopecia as a single manifestation of syphilis infection: clinical and trichoscopic features International Journal of Dermatology · 2018 · 7 citations
    21. Early Diffuse Alopecia in a Neonate with Congenital Syphilis Pediatric Dermatology · 2006 · 7 citations
    22. Alopecia syphilitica diffusa Infection · 2015 · 6 citations
    23. Epidemiological, Clinical, and Trichoscopic Features of Syphilitic Alopecia: A Retrospective Analysis and Systematic Review Frontiers in Medicine · 2022 · 4 citations
    24. Syphilis: today Reviews in Medical Microbiology · 2010 · 2 citations
    25. Moth-eaten alopecia and beyond: Syphilitic alopecia - Revisited Indian Journal of Sexually Transmitted Diseases and AIDS · 2024 · 1 citations
    26. Moth eaten alopecia as the only manifestation of syphilis: a case from Nepal Oxford Medical Case Reports · 2024 · 1 citations
    27. Moth-Eaten Symptomatic Syphilitic Alopecia Associated with Human Immunodeficiency Virus—A Case Report Case Reports in Clinical Medicine · 2016 · 1 citations
    28. DP15 Syphilis: the chameleon disease. A case series of unexpected mimicry British Journal of Dermatology · 2025
    29. Syphilitic Alopecia Through the Dermoscope: A Series of two Cases NATIONAL BOARD OF EXAMINATIONS JOURNAL OF MEDICAL SCIENCES · 2025
    30. Essential syphilitic alopecia: Non-scarring alopecia in 21-year-old man Our Dermatology Online · 2021