Immune Reconstitution Inflammatory Syndrome Associated With Secondary Syphilis: Dermatologic, Neurologic, and Ophthalmologic Compromise in an HIV Patient

    Sami Alcedo, Renee Newby, Juan José Montenegro-Idrogo, Paola L. Rondán, Jorge Arévalo, Alfredo Chiappe-Gonzalez, Jaime Soria
    Studysummary This report discusses a rare case where immune reconstitution inflammatory syndrome in an HIV patient led to dermatologic, ophthalmologic, and neurologic complications due to secondary syphilis. Our plain-language summary of this paper — not a Tressless recommendation.
    The document reported a rare case of immune reconstitution inflammatory syndrome (IRIS) in an HIV patient, presenting with secondary syphilis that affected the skin, eyes, and nervous system. This case highlighted the unusual clinical manifestations of syphilis in the context of IRIS, emphasizing the need for awareness and careful management of such conditions in HIV-infected individuals.
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