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Glossary Nervous System

network transmitting signals between brain, spinal cord, and body

The nervous system, also known as the neural system, is a complex network of nerves and cells that transmit signals between different parts of the body. It consists of the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS), which comprises all other neural elements. This system is essential for coordinating voluntary and involuntary actions, processing sensory information, and maintaining homeostasis.

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Research

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research In vivo evidence for an increase in 5alpha‐reductase activity in the rat central nervous system following morphine exposure

25 citations , September 2005 in “International Journal of Developmental Neuroscience”

This study found that in rats, morphine exposure may increase 5alpha-reductase activity in the CNS, leading to decreased testosterone levels, an effect blocked by finasteride.

research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection

14 citations , February 2003 in “Journal of the American Academy of Dermatology”

This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.

research Increase in testosterone metabolism in the rat central nervous system by formalin-induced tonic pain

11 citations , October 2002 in “Pharmacology Biochemistry and Behavior”

This study found that formalin-induced pain in rats nearly eliminates testosterone in the brain and spinal cord by likely increasing 5α-reductase activity, but normalizes serum levels after 24 hours.

research Central nervous system involvement in autoimmune polyglandular syndrome

10 citations , April 2003 in “Clinical neurology and neurosurgery”

This case study reports a 33-year-old man with autoimmune thyroiditis and alopecia universalis experiencing reversible CNS demyelination, possibly due to autoimmune activity against CNS antigens.

research Central nervous system demyelination associated with tofacitinib use in alopecia areata: A case report and literature review

May 2026 in “Journal of Neurosciences in Rural Practice”

This case report describes a 23-year-old woman with alopecia areata who developed new central nervous system demyelination after starting tofacitinib therapy; while the drug was associated with this neurological event, causality is not confirmed. The demyelination was reversible upon stopping the medication and administering corticosteroids.

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community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

89 upvotes 8 months ago

The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 1 year ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community What happened to topical dutasteride??

in Finasteride/Dutasteride 28 upvotes 1 year ago

Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

community Finasteride is not working

11 upvotes 6 years ago

Finasteride is not effectively stopping hair loss for the user, who is considering alternatives like Dutasteride, Minoxidil, and microneedling, but is hesitant about surgery or hair systems. The user expresses frustration with the lack of effective treatments for male pattern baldness.

community Nothing compensates enough for hair loss at young age.

in Chat 66 upvotes 11 months ago

Early hair loss causes emotional distress, and common coping strategies like fitness and fashion are inadequate. Treatments like finasteride, minoxidil, dutasteride, hair systems, and scalp micropigmentation were tried but were unsatisfactory.

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Learn

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learn Scalp Micropigmentation

Who is a good candidate for scalp micropigmentation? Providers say SMP can suit many kinds of hair loss, but not everyone: active scalp disease, keloid-prone skin, pigment allergy and some medical treatments can rule it out. Get the hair loss diagnosed first.

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