Central Nervous System Involvement in Autoimmune Polyglandular Syndrome

    April 2003 in “ Clinical neurology and neurosurgery ”
    Cavit Boz, Sibel Velioğlu, Vildan Altunayoğlu, Mehmet Özmenoğlu, Cihangir Erem
    TLDR Autoimmune polyglandular syndrome can cause temporary brain issues that may improve on their own.
    The document discussed a case of a 33-year-old man with autoimmune polyglandular syndrome (APS) who presented with unusual central nervous system (CNS) manifestations, specifically decreased vision, which resolved without intervention. This case was notable because CNS involvement in APS had not been previously reported. The patient had a history of alopecia that began at age 17 and progressed to total body hair loss by age 25. The study highlighted the complexity of APS, which involves autoimmune lesions affecting both endocrine and non-endocrine organs, and noted the presence of various organ-specific and non-organ-specific antibodies in APS patients.
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