1 citations
,
January 2014 in “PubMed” This case report describes a 10-year-old child experiencing telogen effluvium as the first symptom of Crohn's disease, highlighting it as a rare extraintestinal manifestation.
33 citations
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June 2012 in “Journal of Crohn's and colitis” This review discusses the role of immune responses, especially Th1 cytokines, in alopecia areata pathogenesis and reports no new research findings.
8 citations
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June 2012 in “Journal of Crohn s and Colitis” This case report documents a 33-year-old male with autoimmune polyglandular syndrome type 2, including diabetes mellitus type 1, Hashimoto thyroiditis, adrenal insufficiency, and Crohn's disease, highlighting the ongoing difficulties in managing multiple autoimmune conditions.
70 citations
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April 2011 in “British journal of dermatology/British journal of dermatology, Supplement” This retrospective study found that methotrexate had variable efficacy in treating severe alopecia areata in children, with successful hair regrowth observed in five out of thirteen assessable cases.
72 citations
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February 2011 in “The American Journal of Dermatopathology” This study found that anti-TNF therapy-induced alopecia exhibits distinct clinical and histopathological features and can mimic psoriatic alopecia and alopecia areata, with some patients improving with topical treatment.
3 citations
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December 2010 in “Annals of tropical paediatrics” In this study, the authors reported that while conventional treatment improved rickets in a boy with vitamin D-dependent rickets type II, it also resulted in unexpected improvement in his alopecia.
72 citations
,
October 2010 in “Journal of The American Academy of Dermatology” This study concluded that iron deficiency is common among women but not more prevalent in those with female pattern hair loss or chronic telogen effluvium compared to control subjects without hair loss.
717 citations
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June 2010 in “Nature” This study identified key genetic regions associated with alopecia areata, highlighting both acquired and innate immune involvement, with a novel link to the upregulation of ULBP ligands in autoimmune disease.
7 citations
,
May 2010 in “Journal of Dermatological Treatment” This case report describes a patient with various conditions, including ulcerative colitis and azathioprine-induced liver injury, and reviews related literature on these coexisting conditions.
244 citations
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January 2010 in “Journal of the American Academy of Dermatology” This review discusses treatment options for alopecia areata and suggests tailored treatment plans, noting the challenges posed by spontaneous remission and limited high-quality clinical trials.
36 citations
,
August 2009 in “PubMed” This article discusses different types of hair loss, their potential causes, and treatment options, but it reports no new clinical findings; the authors emphasize the importance of considering the emotional impact on patients.
88 citations
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June 2009 in “Cleveland Clinic Journal of Medicine” This article reviews various causes of diffuse hair loss, highlighting the importance of identifying triggers through thorough examination for effective treatment and emphasizing patient education in management; it reports no new clinical findings.
21 citations
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January 2009 in “Indian journal of dermatology, venereology, and leprology” Vitamin B12, folate, ferritin, and iron levels are not linked to alopecia areata.
70 citations
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January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews the characteristics, diagnosis, and management of different types of diffuse alopecia in women and provides no original research findings.
45 citations
,
July 2008 in “International Journal of Dermatology” This study found that oral sulfasalazine led to varying hair regrowth outcomes in patients with persistent alopecia areata, with 56.3% showing moderate to good responses.
28 citations
,
February 2008 in “PubMed” This study found that low iron stores are a risk factor for excessive hair loss in non-menopausal women.
39 citations
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July 2007 in “SKINmed Dermatology for the Clinician” In this case study, a 4-year-old girl's hair loss stopped after six months of zinc supplementation and dietary changes, suggesting a possible link to low zinc levels.
11 citations
,
March 2007 in “Digestive Diseases and Sciences” The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.
143 citations
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January 2007 in “The American Journal of Human Genetics” This study identified four genetic loci on chromosomes 6, 10, 16, and 18 that may contribute to susceptibility for alopecia areata and suggested shared genetic factors with psoriasis.
207 citations
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April 2006 in “Journal of The American Academy of Dermatology” This review discusses the complexities of diagnosing and treating iron deficiency related to nutritional anemia and hair loss, concluding that routine screening and supplementation for hair loss are not yet supported by sufficient evidence.
163 citations
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November 2003 in “Journal of Investigative Dermatology” This study found that women with androgenetic alopecia or alopecia areata have significantly lower serum ferritin levels than those without hair loss, suggesting a potential link between these types of alopecia and decreased iron stores.
239 citations
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July 2002 in “Clinical and Experimental Dermatology” This review explores the role of nutritional factors in hair loss, noting that iron and l-lysine supplementation may benefit some individuals, while excessive supplements can lead to hair shedding.
69 citations
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February 2002 in “International Journal of Cosmetic Science” This review discusses genetic and nutritional causes of hair loss, highlighting that around 90% of treated men show noticeable hair regrowth with a dual inhibitor, while women's hair loss may improve by correcting iron and l-lysine deficiencies.
1113 citations
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August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
89 citations
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October 1996 in “Dermatologic Clinics” This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
124 citations
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August 1990 in “British Journal of Dermatology” Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.
4 citations
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May 1989 in “Journal of the Royal Society of Medicine” Crohn's disease can cause hair loss before other symptoms appear.
46 citations
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April 1971 in “American Journal of Clinical Nutrition” Lack of protein causes hair root damage, but it can be reversed by eating protein again.