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research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia

32 citations , August 1999 in “Journal of Investigative Dermatology”

This study found that individuals with early onset extensive androgenetic alopecia have an elevated ratio of DHT to testosterone, but no significant genetic linkage to markers on chromosomes 2 or 5 was detected.

research Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study

11 citations , April 2024 in “Allergy Asthma and Clinical Immunology”

This study found compelling genetic evidence linking atopic and allergic conditions with the development of alopecia areata, suggesting a need for closer monitoring in affected individuals.

research The genetic link between thyroid dysfunction and alopecia areata: a bidirectional two-sample Mendelian randomization study

3 citations , August 2024 in “Frontiers in Endocrinology”

This study offers genetic evidence supporting a causal relationship between thyroid dysfunction and alopecia areata, which may help in managing and treating AA patients.

research Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene LIPH

194 citations , November 2006 in “Science”

This study identified a gene mutation in the LIPH gene associated with inherited hair loss and hair growth defects in certain populations, suggesting lipase H plays a role in hair development.

research Bloch-Sulzberger Syndrome: A Rare X-Linked Dominant Genetic Disorder in a Newborn

1 citations , November 2023 in “Cureus”

This study highlights a case of a 12-day-old female with Bloch-Sulzberger Syndrome, underscoring the need for early diagnosis based on skin symptoms to manage potential complications in other organs effectively.

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community Weight loss drugs linked to increased risk of hair loss, researchers say

in Research/Science 270 upvotes 2 months ago

Weight loss drugs may increase the risk of hair loss, but this is often temporary and influenced by genetics. Treatments like finasteride, minoxidil, and RU58841 are mentioned, with varying effectiveness depending on individual genetic sensitivity to DHT.

community Calling out diffuse thinners here -- Have you ruled out other factors?

in Treatment 54 upvotes 1 year ago

Diffuse hair loss is often linked to genetics but can also be due to health issues like thyroid problems and low vitamin or iron levels. Treatments include finasteride, minoxidil, and dutasteride, with some seeing improvements after addressing health issues.

community Homeless man always wins in this one

1262 upvotes 1 month ago

Hair loss and its potential links to genetics, mental health, and lifestyle factors. Treatments like Minoxidil, finasteride, and RU58841 are not mentioned in the conversation.

community Why Is No One Talking About Chromosome 20?

in Chat 32 upvotes 1 year ago

Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

community I have a theory about hair loss

in Treatment 8 months ago

Hair loss is often linked to inflammation and DHT, with treatments like finasteride, dutasteride, and minoxidil being effective for many. Natural remedies like turmeric and oils are discussed, but medications are generally seen as more reliable for managing genetic hair loss.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Stem Cell Factor

learn Overview

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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