Autoimmune Polyglandular Syndrome Type 2, Alopecia Universalis, and Crohn's Disease

    Marijana Protić, Vladimir Gligorijević, Daniela Bojic, Bojana Popović, Svetozar Damjanović, Njegica Jojić
    TLDR Managing multiple autoimmune diseases in one patient is extremely challenging.
    A 33-year-old male with a history of Crohn's colitis diagnosed in childhood experienced sudden hair loss in 2003, leading to a diagnosis of alopecia universalis. At age 28, he was hospitalized with severe dehydration and ketoacidosis, revealing diabetes mellitus type 1. In 2005, he had a severe relapse of Crohn's disease and was treated with systemic corticosteroids. Despite initial improvement, he developed fatigue, hypotension, and bradycardia, leading to a diagnosis of Hashimoto thyroiditis and adrenal cortex failure. Managing his diabetes, hypothyroidism, adrenal insufficiency, and Crohn's disease proved extremely challenging despite intensive treatment.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hair loss over a year following depression and taking antidepressants

      in Side effects?  199 upvotes 1 week ago
      A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

      community Hairloss all over body and head

      in Treatment  2 upvotes 5 days ago
      A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 1 year ago
      The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

    Similar Research

    5 / 1000+ results