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GlossaryCrohn's disease

chronic inflammation of the gastrointestinal tract

Crohn's disease, also known as regional enteritis or granulomatous colitis, is a chronic inflammatory condition of the gastrointestinal tract. It can affect any part of the digestive system from the mouth to the anus, but most commonly impacts the end of the small intestine (ileum) and the beginning of the colon. Symptoms often include abdominal pain, diarrhea, weight loss, and fatigue. The exact cause is unknown, but it involves an abnormal immune response that leads to inflammation.

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research Failures of DNA Methylation Clocks and Development of a Noise Barometer for Measuring Epigenetic Pressure of Aging and Disease

2 citations, September 2023 in “Aging”

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn’s Disease: Dramatic Improvement After Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies

research Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn’s Disease: Dramatic Improvement After Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies

19 citations, November 2016 in “Dermatology and therapy”

Stopping the medication infliximab and starting new treatments helped a woman's hair grow back and improved her scalp condition.

research Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib

2 citations, November 2021 in “ACG Case Reports Journal”

Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.

research Drug-Associated Alopecia

63 citations, March 1995 in “International Journal of Dermatology”

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

research Genome Scan for Signatures of Adaptive Evolution in Wild African Goat (Capra Nubiana)

October 2023

Wild African goats have genetic adaptations for surviving harsh desert conditions.

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community C’est terrible - at my wits end

in Female 443 upvotes 10 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Autoimmune disease and balding

in Update 12 upvotes 3 months ago

A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

community My Dad seems to get his hair back?

in Question 19 upvotes 5 years ago

A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.

community I talked to urologist about Finasteride and just wanted to share what he said

in Finasteride 229 upvotes 6 years ago

The effects of Finasteride, a drug used to treat hair loss, prostate problems and other conditions. The post by iaskedadoctor describes the conversations they had with a Urologist about the effects of the drug on DHT levels throughout the body, how lower doses are beneficial in reducing side effects, how erectile dysfunction can be psychological as well as physiological, how morning erections are not necessarily important, and how persistent side effects appear to be rare. People also shared their experiences with taking Finasteride for hair loss, including potential side effects such as reduced ejaculate force and development of man boobs.

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