17 citations
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November 1982 in “Annals of Internal Medicine” This report details two cases of accelerated hair loss potentially related to 5-aminosalicylic acid enema therapy in patients with ulcerative proctitis.
March 1983 in “Annals of Internal Medicine” This letter to the editor mentions reports of hair loss potentially related to 5-aminosalicylic acid enemas, but suggests it may be due to telogen effluvium from severe inflammatory bowel disease rather than a direct effect.
53 citations
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August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
51 citations
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August 2015 in “Cochrane library” This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.
68 citations
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April 2012 in “Digestive and Liver Disease” This study found that both Elental and 6-mercaptopurine were effective for maintaining remission in Crohn's disease, without a significant difference between them over 24 months.