TLDR 5-aminosalicylic acid enemas may cause hair loss.
The document reported two cases of accelerated hair loss associated with the use of 5-aminosalicylic acid enemas for treating ulcerative proctitis. This was notable because 5-aminosalicylic acid, unlike its precursor sulfasalazine, was believed to be free of side effects. The cases involved a 24-year-old man with idiopathic distal ulcerative colitis, suggesting a potential side effect of hair loss from this treatment, which was previously considered unlikely.
53 citations,
August 2014 in “Cochrane library” Methotrexate is not proven effective for inducing remission in ulcerative colitis.
1 citations,
September 2022 in “BioNanoScience” Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.
51 citations,
August 2015 in “Cochrane library” Methotrexate is not proven to maintain remission in ulcerative colitis.
18 citations,
April 2013 in “Inflammatory Bowel Diseases” People with Inflammatory Bowel Disease often lose hair due to stress, medication side effects, or lack of nutrients, and treatment depends on the specific cause.
63 citations,
March 1995 in “International Journal of Dermatology” Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.