Clinical Case of Tofacitinib Therapy in Autoimmune Alopecia in Patient with Ulcerative Colitis

    September 2022 in “ BioNanoScience ”
    E. S. BODRYAGINA, А. Х. Одинцова, Natalia Cheremina, Nataliya L. Blatt, Д. Р. Акберова, Д. И. Абдулганиева
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    TLDR Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.
    The document discusses a clinical case where a patient with ulcerative colitis, sacroiliitis, and alopecia was treated with the Janus kinase inhibitor, tofacitinib. This treatment led to disease remission, reduced activity of ulcerative colitis and sacroiliitis, and the resumption of hair growth. However, when the dose of tofacitinib was reduced to 10 mg/day, the patient experienced hair loss again, despite the remission of ulcerative colitis being maintained. The document concludes that tofacitinib therapy can effectively stimulate hair growth in alopecia patients, but hair loss may recur if the therapy is stopped or reduced.
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      in Chat  35 upvotes 10 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  865 upvotes 9 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 3 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Topical solution recommendation

      in Treatment  1 upvotes 3 days ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 4 days ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

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