Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn’s Disease: Dramatic Improvement After Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies

A 23-year-old female with Crohn's disease who developed severe alopecia and scalp psoriasis after treatment with infliximab experienced complete hair regrowth and recovery of her scalp condition within 4 months following the cessation of infliximab and the start of treatment with oral minocycline and various topical therapies. The case underscores the need for prompt diagnosis and treatment of alopecia related to tumor necrosis factor alpha antagonist therapy to avert permanent hair loss. The patient's hair and scalp health remained stable after switching to ustekinumab for her Crohn's disease, suggesting the importance of stopping the causative medication and applying aggressive adjuvant treatments to reverse adverse effects.