TLDR TNF-inhibitor induced alopecia can be treated effectively with different therapies.
The document discussed cases of alopecia induced by TNF inhibitors used to treat Crohn disease and psoriasis. It described a woman who developed alopecia and scalp psoriasis during infliximab therapy, which resolved after discontinuing the drug and starting oral and topical treatments. The study compared this case with another where alopecia was induced by adalimumab, noting different histopathologic features. Both patients fully recovered, but with different treatment approaches: one continued adalimumab with intralesional triamcinolone acetonide, while the other discontinued infliximab and used topical therapies and oral minocycline. The conclusion emphasized the variability in histopathology and the effectiveness of multiple therapeutic options for TNF-inhibitor induced alopecia.
19 citations,
November 2016 in “Dermatology and therapy” Stopping the medication infliximab and starting new treatments helped a woman's hair grow back and improved her scalp condition.
42 citations,
March 2015 in “Anais Brasileiros de Dermatologia” Anti-TNF therapy can cause hair loss and skin issues.
254 citations,
December 2003 in “Journal of the American Academy of Dermatology” Accurate diagnosis and aggressive treatment are crucial to prevent permanent hair loss in cicatricial alopecia.
2 citations,
January 2014 in “Journal of clinical and investigative dermatology” Some drugs used to treat immune conditions may cause different types of hair loss.
278 citations,
March 2013 in “Gut” Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
A girl with Crohn's disease developed hair loss due to her increased medication, a rare side effect seen in some children.
1 citations,
April 2012 in “Informa Healthcare eBooks” Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.
72 citations,
February 2011 in “The American Journal of Dermatopathology” Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.
