Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors

    January 2014 in “ Journal of clinical and investigative dermatology ”
    Antonella Tosti
    Studysummary This article reviews TNF-α inhibitor-induced alopecia, identifying various types of hair loss such as severe alopecia areata and scarring alopecia, and calls for more controlled studies to better understand this adverse effect.
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    Research cited in this study 8

    1. Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature Dermatology · 2012
    2. Weight Gain and Hair Loss During Anti-TNF Therapy International Journal of Rheumatology · 2012
    3. Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia The American Journal of Dermatopathology · 2011
    4. Alopecia Areata as Another Immune-Mediated Disease Developed in Patients Treated with Tumor Necrosis Factor-Alpha Blocker Agents Journal of the European Academy of Dermatology and Venereology · 2010
    5. Alopecia Areata Following Adalimumab Journal of Cutaneous Medicine and Surgery · 2009
    6. Onset of Lichen Planopilaris During Treatment with Etanercept British Journal of Dermatology · 2008
    7. Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab Archives of dermatology · 2006
    8. Recurrence of Alopecia Areata in a Patient Receiving Etanercept Injections Archives of Dermatology · 2005