Recurrence of Alopecia Areata in a Patient Receiving Etanercept Injections

June 2005 in “ Archives of Dermatology ”

William Posten, James Swan

alopecia areata etanercept TNF-α tumor necrosis factor alpha rheumatoid arthritis Enbrel

TLDR Etanercept may not prevent alopecia areata from coming back.

The document described a case of a 49-year-old man with rheumatoid arthritis and a history of alopecia areata who experienced a recurrence of alopecia areata while being treated with etanercept, a TNF-α blocker, for over 2 years. Despite the known association of alopecia areata with autoimmune mechanisms and the involvement of TNF-α, the recurrence during etanercept therapy suggested that TNF-α might not be essential in the disease's pathogenesis. This case highlighted the complexity of alopecia areata and the need for further research to understand its underlying mechanisms.

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research Recurrence of Alopecia Areata in a Patient Receiving Etanercept Injections

75 citations, June 2005 in “Archives of Dermatology”

Etanercept may not prevent alopecia areata from coming back.