Perifolliculitis Capitis Abscedens Et Suffodiens Treatment With Tumor Necrosis Factor Inhibitors and Baricitinib: A Case Report and Literature Review

    March 2023 in “ Frontiers in medicine
    Yuanting Yu, Xiaojie Ding, Fei Guo, Ze Kan, Xinghuai Sun, Xin Li
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    TLDR A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.
    A 15-year-old boy with perifolliculitis capitis abscedens et suffodiens (PCAS) was treated with a combination of adalimumab and baricitinib after initial treatment with adalimumab and isotretinoin proved insufficient. Over 9 months, the patient's condition significantly improved, with almost complete healing of skin lesions and disappearance of most inflammatory alopecia patches. This case represents the first documented successful treatment of PCAS using tumor necrosis factor inhibitors and baricitinib, as no previous reports were found in the literature.
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