Alopecia Universalis Under Adalimumab Therapy in a Patient with Rheumatoid Arthritis

    May 2018 in “ Zeitschrift für Rheumatologie ”
    Predrag Ostojić, Slavica Pavlov-Dolijanović
    TLDR A woman with rheumatoid arthritis lost all her hair during adalimumab treatment, and stopping the drug didn't help.
    A 56-year-old female patient with rheumatoid arthritis developed alopecia universalis, a complete loss of hair, during treatment with the TNF-α inhibitor adalimumab. Despite discontinuing adalimumab, her alopecia did not improve. The study suggested that interferon-α might play a key role in the inflammation process leading to hair loss after TNF-α inhibition. The risk/benefit ratio of continuing or stopping TNF inhibitors should be carefully considered when alopecia occurs during treatment.
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